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An effective approach to prevent immune rejection of human ESC-derived allografts

Human embryonic stem cells (hESCs) hold great promise for cell therapy as a source of diverse differentiated cell types. One key bottleneck to realizing such potential is allogenic immune rejection of hESC-derived cells by recipients. Here, we optimized humanized mice (Hu-mice) reconstituted with a...

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Detalhes bibliográficos
Main Authors: Rong, Zhili, Wang, Meiyan, Hu, Zheng, Stradner, Martin, Zhu, Shengyun, Kong, Huijuan, Yi, Huanfa, Goldrath, Ananda, Yang, Yong-Guang, Xu, Yang, Fu, Xuemei
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023958/
https://ncbi.nlm.nih.gov/pubmed/24388175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2013.11.014
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