High expression of IGFBP2 is associated with chemoresistance in adult acute myeloid leukemia

Insulin-like growth factor (IGF) signaling plays an important role in many tumors and overexpression of IGF Binding Protein (IGFBP) 2 has been associated with adverse outcome in childhood leukemia. Here, we evaluated IGFBP2 mRNA expression and its prognostic implications in 99 adult acute myeloid le...

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Main Authors: Kühnl, Andrea, Kaiser, Martin, Neumann, Martin, Fransecky, Lars, Heesch, Sandra, Radmacher, Michael, Marcucci, Guido, Bloomfield, Clara D, Hofmann, Wolf-Karsten, Thiel, Eckhard, Baldus, Claudia D
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023812/
https://ncbi.nlm.nih.gov/pubmed/21899885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2011.08.006
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