Efflux pump of the proton antiporter family confers low-level fluoroquinolone resistance in Mycobacterium smegmatis.

Due to the resurgence of tuberculosis and the emergence of multidrug-resistant strains, fluoroquinolones (FQ) are being used in selected tuberculosis patients, but FQ-resistant strains of Mycobacterium tuberculosis have rapidly begun to appear. The mechanisms involved in FQ resistance need to be elu...

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Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Takiff, H E, Cimino, M, Musso, M C, Weisbrod, T, Martinez, R, Delgado, M B, Salazar, L, Bloom, B R, Jacobs, W R
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1996
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40238/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8552639/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.1.362
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