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Evaluation of Acanthamoeba Myosin-IC as a Potential Therapeutic Target

Members of the genus Acanthamoeba are facultative pathogens of humans, causing a sight-threatening keratitis and a fatal encephalitis. We have targeted myosin-IC by using small interfering RNA (siRNA) silencing as a therapeutic approach, since it is known that the function of this protein is vital f...

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Auteurs principaux: Martín-Navarro, Carmen M., Lorenzo-Morales, Jacob, López-Arencibia, Atteneri, Reyes-Batlle, María, Piñero, José E., Valladares, Basilio, Maciver, Sutherland K.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023789/
https://ncbi.nlm.nih.gov/pubmed/24468784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01199-13
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