CYP2B6 18492T→C Polymorphism Compromises Efavirenz Concentration in Coinfected HIV and Tuberculosis Patients Carrying CYP2B6 Haplotype *1/*1

Data regarding the effect of the CYP2B6 18492T→C polymorphism on plasma efavirenz concentrations and 96-week virologic responses in patients coinfected with HIV and tuberculosis (TB) are still unavailable. A total of 139 antiretroviral-naive HIV-infected adults with active TB were prospectively enro...

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Bibliografiska uppgifter
Huvudupphovsmän: Manosuthi, Weerawat, Sukasem, Chonlaphat, Thongyen, Supeda, Nilkamhang, Samruay, Manosuthi, Sukanya, Sungkanuparph, Somnuek
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2014
Ämnen:
Antiviral Agents
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023787/
https://ncbi.nlm.nih.gov/pubmed/24492364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02384-13
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