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Post-β-Lactamase-Inhibitor Effect of Tazobactam in Combination with Ceftolozane on Extended-Spectrum-β-Lactamase-Producing Strains

The post-β-lactamase-inhibitor effect (PBLIE) of tazobactam combined with ceftolozane was evaluated by time-kill assays on two clinical Escherichia coli strains producing CTX-M-15 with or without TEM-1. The organisms were exposed (2 h) to 4 μg/ml/4 μg/ml of ceftolozane-tazobactam (4× MIC), 4 μg/ml o...

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Bibliografske podrobnosti
Main Authors: Sader, Helio S., Rhomberg, Paul R., Jones, Ronald N.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023764/
https://ncbi.nlm.nih.gov/pubmed/24449780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02398-13
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