Alkyl Galactofuranosides Strongly Interact with Leishmania donovani Membrane and Provide Antileishmanial Activity

We investigated the in vitro effects of four alkyl-galactofuranoside derivatives, i.e., octyl-β-d-galactofuranoside (compound 1), 6-amino-β-d-galactofuranoside (compound 2), 6-N-acetamido-β-d-galactofuranoside (compound 3), and 6-azido-β-d-galactofuranoside (compound 4), on Leishmania donovani. Thei...

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Hauptverfasser: Suleman, Muhammad, Gangneux, Jean-Pierre, Legentil, Laurent, Belaz, Sorya, Cabezas, Yari, Manuel, Christelle, Dureau, Rémy, Sergent, Odile, Burel, Agnès, Daligault, Franck, Ferrières, Vincent, Robert-Gangneux, Florence
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
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Mechanisms of Action: Physiological Effects
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023744/
https://ncbi.nlm.nih.gov/pubmed/24468785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01350-13
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