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Multiplex analysis of mitochondrial DNA pathogenic and polymorphic sequence variants
The mitochondrial DNA (mtDNA) encompasses two classes of functionally important sequence variants: recent pathogenic mutations and ancient adaptive polymorphisms. To rapidly and cheaply evaluate both classes of single nucleotide variants (SNVs), we have developed an integrated system in which mtDNA...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4023691/ https://ncbi.nlm.nih.gov/pubmed/20707610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/BC.2010.125 |
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