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The Role Of Extracellular Matrix Elasticity and Composition In Regulating the Nucleus Pulposus Cell Phenotype in the Intervertebral Disc: A Narrative Review

Intervertebral disc (IVD) disorders are a major contributor to disability and societal health care costs. Nucleus pulposus (NP) cells of the IVD exhibit changes in both phenotype and morphology with aging-related IVD degeneration that may impact the onset and progression of IVD pathology. Studies ha...

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Autores principales: Hwang, Priscilla Y., Chen, Jun, Jing, Liufang, Hoffman, Brenton D., Setton, Lori A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Mechanical Engineers 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023659/
https://ncbi.nlm.nih.gov/pubmed/24390195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1115/1.4026360
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