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Identification of an Intermediate Methyl Carrier in the Radical SAM Methylthiotransferases, RimO and MiaB
RimO and MiaB are radical S-adenosylmethionine (SAM) enzymes that catalyze the attachment of methylthio (–SCH(3)) groups onto macromolecular substrates. RimO attaches a methylthio group at C3 of aspartate 89 of protein S12, a component of the 30S subunit of the bacterial ribosome. MiaB attaches a me...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4023531/ https://ncbi.nlm.nih.gov/pubmed/23991893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4048448 |
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