Longitudinal imaging pattern analysis (SPARE-CD index) detects early structural and functional changes before cognitive decline in healthy older adults

This article investigates longitudinal imaging characteristics of early cognitive decline during normal aging, leveraging on high-dimensional imaging pattern classification methods for the development of early biomarkers of cognitive decline. By combining magnetic resonance imaging (MRI) and resting...

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Autori principali: Clark, Vanessa H., Resnick, Susan M., Doshi, Jimit, Beason-Held, Lori L., Zhou, Yun, Ferrucci, Luigi, Wong, Dean F., Kraut, Michael A., Davatzikos, Christos
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023476/
https://ncbi.nlm.nih.gov/pubmed/22365049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2012.01.010
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