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Regulation of steatohepatitis and PPARγ signaling by distinct AP-1 dimers
Non-alcoholic fatty liver disease (NAFLD) affects up to 30% of the adult population in Western societies, yet the underlying molecular pathways remain poorly understood. Here, we identify the dimeric Activator Protein 1 as a regulator of NAFLD. The Fos-related antigen 1 (Fra-1) and 2 (Fra-2) prevent...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4023468/ https://ncbi.nlm.nih.gov/pubmed/24411941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.11.018 |
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