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Multi-Target Directed Drugs: A Modern Approach for Design of New Drugs for the treatment of Alzheimer’s Disease

Alzheimer’s disease (AD) is a complex neurodegenerative disorder with a multi-faceted pathogenesis. So far, the therapeutic paradigm “one-compound-one-target” has failed and despite enormous efforts to elucidate the pathophysiology of AD, the disease is still incurable. The multiple factors involved...

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Détails bibliographiques
Auteurs principaux: Dias, Kris Simone Tranches, Viegas, Jr, Claudio
Format: Artigo
Langue:Inglês
Publié: Bentham Science Publishers 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023454/
https://ncbi.nlm.nih.gov/pubmed/24851088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1570159X1203140511153200
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