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A role of amphiphysin in synaptic vesicle endocytosis suggested by its binding to dynamin in nerve terminals.

Amphiphysin, a major autoantigen in paraneoplastic Stiff-Man syndrome, is an SH3 domain-containing neuronal protein, concentrated in nerve terminals. Here, we demonstrate a specific, SH3 domain-mediated, interaction between amphiphysin and dynamin by gel overlay and affinity chromatography. In addit...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: David, C, McPherson, P S, Mundigl, O, de Camilli, P
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40232/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8552632/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.1.331
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