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Comparison of intervention effects in split-mouth and parallel-arm randomized controlled trials: a meta-epidemiological study

BACKGROUND: Split-mouth randomized controlled trials (RCTs) are popular in oral health research. Meta-analyses frequently include trials of both split-mouth and parallel-arm designs to derive combined intervention effects. However, carry-over effects may induce bias in split- mouth RCTs. We aimed to...

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Detalhes bibliográficos
Main Authors: Smaïl-Faugeron, Violaine, Fron-Chabouis, Hélène, Courson, Frédéric, Durieux, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023173/
https://ncbi.nlm.nih.gov/pubmed/24886043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2288-14-64
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