Role of plasma matrix-metalloproteases (MMPs) and their polymorphisms (SNPs) in sepsis development and outcome in ICU patients

Matrix-metalloproteases (MMPs) and their tissue-inhibitors (TIMPs), modulated by different single nucleotide polymorphisms (SNPs), are critical in sepsis development. Ninety ICU severely septic and 91 ICU uninfected patients were prospectively studied. MMP-1 (−1607 1G/2G), MMP-3 (−1612 5A/6A), MMP-8...

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Detalhes bibliográficos
Main Authors: Martin, Guadalupe, Asensi, Víctor, Montes, A. Hugo, Collazos, Julio, Alvarez, Victoria, Carton, José A., Taboada, Francisco, Valle-Garay, Eulalia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023133/
https://ncbi.nlm.nih.gov/pubmed/24833564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05002
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