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Design principles of stripe-forming motifs: the role of positive feedback

Interpreting a morphogen gradient into a single stripe of gene-expression is a fundamental unit of patterning in early embryogenesis. From both experimental data and computational studies the feed-forward motifs stand out as minimal networks capable of this patterning function. Positive feedback wit...

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Bibliografiske detaljer
Main Authors: Munteanu, Andreea, Cotterell, James, Solé, Ricard V., Sharpe, James
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023129/
https://ncbi.nlm.nih.gov/pubmed/24830352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05003
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