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An integrated computational model of the bone microenvironment in bone-metastatic prostate cancer

Bone metastasis will impact most men with advanced prostate cancer. The vicious cycle of bone degradation and formation driven by metastatic prostate cells in bone yields factors that drive cancer growth. Mechanistic insights into this vicious cycle have suggested new therapeutic opportunities, but...

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Detalhes bibliográficos
Main Authors: Araujo, Arturo, Cook, Leah M., Lynch, Conor C., Basanta, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023121/
https://ncbi.nlm.nih.gov/pubmed/24788098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-2652
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