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An integrated computational model of the bone microenvironment in bone-metastatic prostate cancer

Bone metastasis will impact most men with advanced prostate cancer. The vicious cycle of bone degradation and formation driven by metastatic prostate cells in bone yields factors that drive cancer growth. Mechanistic insights into this vicious cycle have suggested new therapeutic opportunities, but...

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Hlavní autoři: Araujo, Arturo, Cook, Leah M., Lynch, Conor C., Basanta, David
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023121/
https://ncbi.nlm.nih.gov/pubmed/24788098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-2652
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