Toll-like Receptor-mediated Down-regulation of the Deubiquitinase Cylindromatosis (CYLD) Protects Macrophages from Necroptosis in Wild-derived Mice

Pathogen recognition by the innate immune system initiates the production of proinflammatory cytokines but can also lead to programmed host cell death. Necroptosis, a caspase-independent cell death pathway, can contribute to the host defense against pathogens or cause damage to host tissues. Recepto...

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Detaylı Bibliyografya
Asıl Yazarlar: Schworer, Stephen A., Smirnova, Irina I., Kurbatova, Irina, Bagina, Uliana, Churova, Maria, Fowler, Trent, Roy, Ananda L., Degterev, Alexei, Poltorak, Alexander
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2014
Konular:
Immunology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022908/
https://ncbi.nlm.nih.gov/pubmed/24706750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.547547
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