Neuron-derived Neurotrophic Factor Functions as a Novel Modulator That Enhances Endothelial Cell Function and Revascularization Processes

Strategies to stimulate revascularization are valuable for cardiovascular diseases. Here we identify neuron-derived neurotrophic factor (NDNF)/epidermacan as a secreted molecule that is up-regulated in endothelial cells in ischemic limbs of mice. NDNF was secreted from cultured human endothelial cel...

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Hlavní autoři: Ohashi, Koji, Enomoto, Takashi, Joki, Yusuke, Shibata, Rei, Ogura, Yasuhiro, Kataoka, Yoshiyuki, Shimizu, Yuuki, Kambara, Takahiro, Uemura, Yusuke, Yuasa, Daisuke, Matsuo, Kazuhiro, Hayakawa, Satoko, Hiramatsu-Ito, Mizuho, Murohara, Toyoaki, Ouchi, Noriyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022881/
https://ncbi.nlm.nih.gov/pubmed/24706764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.555789
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