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Antibodies against specific extracellular epitopes of the glucagon receptor block glucagon binding.

Polyclonal antibodies were prepared against synthetic peptides corresponding to four different extramembrane segments of the rat glucagon receptor. The antibodies bound specifically to native glucagon receptor as judged by immunofluorescence microscopy of cultured cells expressing a synthetic gene f...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Unson, C G, Cypess, A M, Wu, C R, Goldsmith, P K, Merrifield, R B, Sakmar, T P
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1996
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40228/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8552628/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.1.310
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