Immune Humanization of Immunodeficient Mice Using Diagnostic Bone Marrow Aspirates from Carcinoma Patients

Tumor xenografts in immunodeficient mice, while routinely used in cancer research, preclude studying interactions of immune and cancer cells or, if humanized by allogeneic immune cells, are of limited use for tumor-immunological questions. Here, we explore a novel way to generate cancer models with...

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Главные авторы: Werner-Klein, Melanie, Proske, Judith, Werno, Christian, Schneider, Katharina, Hofmann, Hans-Stefan, Rack, Brigitte, Buchholz, Stefan, Ganzer, Roman, Blana, Andreas, Seelbach-Göbel, Birgit, Nitsche, Ulrich, Männel, Daniela N., Klein, Christoph A.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022674/
https://ncbi.nlm.nih.gov/pubmed/24830425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097860
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