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The C-Terminal Random Coil Region Tunes the Ca(2+)-Binding Affinity of S100A4 through Conformational Activation
S100A4 interacts with many binding partners upon Ca(2+) activation and is strongly associated with increased metastasis formation. In order to understand the role of the C-terminal random coil for the protein function we examined how small angle X-ray scattering of the wild-type S100A4 and its C-ter...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4022583/ https://ncbi.nlm.nih.gov/pubmed/24830809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097654 |
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