Interactions between Exosomes from Breast Cancer Cells and Primary Mammary Epithelial Cells Leads to Generation of Reactive Oxygen Species Which Induce DNA Damage Response, Stabilization of p53 and Autophagy in Epithelial Cells

Exosomes are nanovesicles originating from multivesicular bodies and are released by all cell types. They contain proteins, lipids, microRNAs, mRNAs and DNA fragments, which act as mediators of intercellular communications by inducing phenotypic changes in recipient cells. Tumor-derived exosomes hav...

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Hauptverfasser: Dutta, Sujoy, Warshall, Case, Bandyopadhyay, Chirosree, Dutta, Dipanjan, Chandran, Bala
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022578/
https://ncbi.nlm.nih.gov/pubmed/24831807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097580
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