In-Vivo Real-Time Control of Protein Expression from Endogenous and Synthetic Gene Networks

We describe an innovative experimental and computational approach to control the expression of a protein in a population of yeast cells. We designed a simple control algorithm to automatically regulate the administration of inducer molecules to the cells by comparing the actual protein expression le...

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Main Authors: Menolascina, Filippo, Fiore, Gianfranco, Orabona, Emanuele, De Stefano, Luca, Ferry, Mike, Hasty, Jeff, di Bernardo, Mario, di Bernardo, Diego
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022480/
https://ncbi.nlm.nih.gov/pubmed/24831205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003625
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