NQO1 gene rs1800566 variant is not associated with risk for multiple sclerosis

BACKGROUND: A possible role of oxidative stress in the pathogenesis of multiple sclerosis (MS) and in experimental autoimmune encephalomyelitis has been suggested. The detoxification enzyme NAD(P)H dehydrogenase, quinone 1 (NQO1) has been found up-regulated in MS lesions. A previous report described...

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Main Authors: Agúndez, José A G, García-Martín, Elena, Martínez, Carmen, Benito-León, Julián, Millán-Pascual, Jorge, Calleja, Patricia, Díaz-Sánchez, María, Pisa, Diana, Turpín-Fenoll, Laura, Alonso-Navarro, Hortensia, Ayuso-Peralta, Lucía, Torrecillas, Dolores, Plaza-Nieto, José Francisco, Jiménez-Jiménez, Félix Javier
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022329/
https://ncbi.nlm.nih.gov/pubmed/24755231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2377-14-87
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