Perturbation of specific pro-mineralizing signalling pathways in human and murine pseudoxanthoma elasticum

BACKGROUND: Pseudoxanthoma elasticum (PXE) is characterized by skin (papular lesions), ocular (subretinal neovascularisation) and cardiovascular manifestations (peripheral artery disease), due to mineralization and fragmentation of elastic fibres in the extracellular matrix (ECM). Caused by mutation...

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Detalhes bibliográficos
Main Authors: Hosen, Mohammad J, Coucke, Paul J, Le Saux, Olivier, De Paepe, Anne, Vanakker, Olivier M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022264/
https://ncbi.nlm.nih.gov/pubmed/24775865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1172-9-66
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