A patient tumor-derived orthotopic xenograft mouse model replicating the group 3 supratentorial primitive neuroectodermal tumor in children

BACKGROUND: Supratentorial primitive neuroectodermal tumor (sPNET) is a malignant brain tumor with poor prognosis. New model systems that replicate sPNET's molecular subtype(s) and maintain cancer stem cell (CSC) pool are needed. METHODS: A fresh surgical specimen of a pediatric sPNET was direc...

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Detalhes bibliográficos
Main Authors: Liu, Zhigang, Zhao, Xiumei, Wang, Yue, Mao, Hua, Huang, Yulun, Kogiso, Mari, Qi, Lin, Baxter, Patricia A., Man, Tsz-Kwong, Adesina, Adekunle, Su, Jack M., Picard, Daniel, Ching Ho, King, Huang, Annie, Perlaky, Laszlo, Lau, Ching C., Chintagumpala, Murali, Li, Xiao-Nan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022216/
https://ncbi.nlm.nih.gov/pubmed/24470556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not244
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