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Global transcript and phenotypic analysis of yeast cells expressing Ssa1, Ssa2, Ssa3 or Ssa4 as sole source of cytosolic Hsp70-Ssa chaperone activity

BACKGROUND: Cytosolic Hsp70 is a ubiquitous molecular chaperone that is involved in responding to a variety of cellular stresses. A major function of Hsp70 is to prevent the aggregation of denatured proteins by binding to exposed hydrophobic regions and preventing the accumulation of amorphous aggre...

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Detalhes bibliográficos
Main Authors: Hasin, Naushaba, Cusack, Sarah A, Ali, Shahin S, Fitzpatrick, David A, Jones, Gary W
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022180/
https://ncbi.nlm.nih.gov/pubmed/24628813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-194
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