Mas-Mediated Antioxidant Effects Restore the Functionality of Angiotensin Converting Enzyme 2-Angiotensin-(1–7)-Mas Axis in Diabetic Rat Carotid

We hypothesized that endothelial AT(1)-activated NAD(P)H oxidase-driven generation of reactive oxygen species during type I-diabetes impairs carotid ACE2-angiotensin-(1–7)-Mas axis functionality, which accounts for the impaired carotid flow in diabetic rats. We also hypothesized that angiotensin-(1–...

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Autors principals: Pernomian, Larissa, Gomes, Mayara Santos, Restini, Carolina Baraldi Araujo, de Oliveira, Ana Maria
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022170/
https://ncbi.nlm.nih.gov/pubmed/24877125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/640329
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