Homeobox Genes and Melatonin Synthesis: Regulatory Roles of the Cone-Rod Homeobox Transcription Factor in the Rodent Pineal Gland

Nocturnal synthesis of melatonin in the pineal gland is controlled by a circadian rhythm in arylalkylamine N-acetyltransferase (AANAT) enzyme activity. In the rodent, Aanat gene expression displays a marked circadian rhythm; release of norepinephrine in the gland at night causes a cAMP-based inducti...

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Hlavní autoři: Rohde, Kristian, Møller, Morten, Rath, Martin Fredensborg
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2014
Témata:
Review Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022116/
https://ncbi.nlm.nih.gov/pubmed/24877149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/946075
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