A rat decellularized small bowel scaffold that preserves villus-crypt architecture for intestinal regeneration

Management of intestinal failure remains a clinical challenge and total parenteral nutrition, intestinal elongation and/or transplantation are partial solutions. In this study, using a detergent-enzymatic treatment (DET), we optimize in rats a new protocol that creates a natural intestinal scaffold,...

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Main Authors: Totonelli, Giorgia, Maghsoudlou, Panagiotis, Garriboli, Massimo, Riegler, Johannes, Orlando, Giuseppe, Burns, Alan J., Sebire, Neil J., Smith, Virpi V., Fishman, Jonathan M., Ghionzoli, Marco, Turmaine, Mark, Birchall, Martin A., Atala, Anthony, Soker, Shay, Lythgoe, Mark F., Seifalian, Alexander, Pierro, Agostino, Eaton, Simon, De Coppi, Paolo
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Science 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022101/
https://ncbi.nlm.nih.gov/pubmed/22305104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.01.012
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