CD45RA(-)Foxp3(high) but not CD45RA(+)Foxp3(low) suppressive T regulatory cells increased in the peripheral circulation of patients with head and neck squamous cell carcinoma and correlated with tumor progression

BACKGROUND: T regulatory cells (Tregs) contribute to the progression of head and neck squamous cell carcinoma (HNSCC) by suppressing antitumor immunity. However, little is known regarding the functional heterogeneity of Tregs in HNSCC patients. METHODS: Using multicolor flow cytometry, the frequency...

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Hauptverfasser: Sun, Wei, Li, Wei-Jin, Wu, Chang-You, Zhong, Hua, Wen, Wei-Ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022051/
https://ncbi.nlm.nih.gov/pubmed/24761979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-33-35
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