Notch and Hedgehog Signaling Cooperate to Maintain Self-Renewal of Human Embryonic Stem Cells Exposed to Low Oxygen Concentration

BACKGROUND AND OBJECTIVES: Expansion and maintenance of human embryonic stem cells (hESCs) in undifferentiated state is influenced by complex signals in the microenvironment, including those contingent upon oxygen availability. Responses mediated by Notch and Hedgehog (Hh) have essential role in the...

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Autori principali: Weli, Simon C., Fink, Trine, Cetinkaya, Cihan, Prasad, Mayuri S., Pennisi, Cristian P., Zachar, Vladimir
Natura: Artigo
Lingua:Inglês
Pubblicazione: Korean Society for Stem Cell Research 2010
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021806/
https://ncbi.nlm.nih.gov/pubmed/24855550
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