CopyRighter: a rapid tool for improving the accuracy of microbial community profiles through lineage-specific gene copy number correction

BACKGROUND: Culture-independent molecular surveys targeting conserved marker genes, most notably 16S rRNA, to assess microbial diversity remain semi-quantitative due to variations in the number of gene copies between species. RESULTS: Based on 2,900 sequenced reference genomes, we show that 16S rRNA...

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Detaylı Bibliyografya
Asıl Yazarlar: Angly, Florent E, Dennis, Paul G, Skarshewski, Adam, Vanwonterghem, Inka, Hugenholtz, Philip, Tyson, Gene W
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2014
Konular:
Methodology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021573/
https://ncbi.nlm.nih.gov/pubmed/24708850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2049-2618-2-11
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