Molecular staging of lymph node-negative colon carcinomas by one-step nucleic acid amplification (OSNA) results in upstaging of a quarter of patients in a prospective, European, multicentre study

BACKGROUND: Current histopathological staging procedures in colon carcinomas depend on midline division of the lymph nodes with one section of haematoxylin & eosin (H&E) staining only. By this method, tumour deposits outside this transection line may be missed and could lead to understaging...

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Detalhes bibliográficos
Main Authors: Croner, R S, Geppert, C-I, Bader, F G, Nitsche, U, Späth, C, Rosenberg, R, Zettl, A, Matias-Guiu, X, Tarragona, J, Güller, U, Stürzl, M, Zuber, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021519/
https://ncbi.nlm.nih.gov/pubmed/24722182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.170
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