Rapid decline of chronic myeloid leukemic cells in long-term culture due to a defect at the leukemic stem cell level.

In this report we describe a quantitative in vitro assay for the most primitive type of leukemic precursors yet defined in patients with chronic myeloid leukemia (CML). This assay is based on the recently described "long-term culture-initiating cell" (LTC-IC) assay for primitive normal hum...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Udomsakdi, C, Eaves, C J, Swolin, B, Reid, D S, Barnett, M J, Eaves, A C
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC402148/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1631107/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.13.6192
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