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Amyloid-beta neuroprotection mediated by a targeted antioxidant

Amyloid-beta (Aβ)-induced neurotoxicity is a major contributor to the pathologies associated with Alzheimer's disease (AD). The formation of reactive oxygen species (ROS), an early response induced by the peptide and oligomeric derivatives of Aβ, plays a significant role in effecting cellular p...

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Detalhes bibliográficos
Main Authors: Giordano, Courtney R., Terlecky, Laura J., Bollig-Fischer, Aliccia, Walton, Paul A., Terlecky, Stanley R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021325/
https://ncbi.nlm.nih.gov/pubmed/24828380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04983
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