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Emerging modes of PINK1 signaling: another task for MARK2

PTEN-induced kinase 1 (PINK1) acts at multiple levels to promote mitochondrial health, including regulatory influence on ATP-synthesis, protein quality control, apoptosis, mitochondrial transport, and destiny. PINK1 mutations are linked to Parkinson disease (PD) and mostly result in loss of kinase a...

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Detalhes bibliográficos
Main Authors: Matenia, Dorthe, Mandelkow, Eva M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021145/
https://ncbi.nlm.nih.gov/pubmed/24847206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2014.00037
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