Potent immunogenicity of the B subunits of Escherichia coli heat-labile enterotoxin: receptor binding is essential and induces differential modulation of lymphocyte subsets.

The importance of receptor binding in the potent immunogenicity of Escherichia coli heat-labile enterotoxin B subunit (EtxB) was tested by comparing its immunogical properties with those of a receptor binding mutant, EtxB(G33D). Subcutaneous immunization of EtxB(G33D) resulted in 160-fold reduction...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Nashar, T O, Webb, H M, Eaglestone, S, Williams, N A, Hirst, T R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1996
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40211/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8552610/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.1.226
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