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Breast tumor specific mutation in GATA3 affects physiological mechanisms regulating transcription factor turnover
BACKGROUND: The transcription factor GATA3 is a favorable prognostic indicator in estrogen receptor-α (ERα)-positive breast tumors in which it participates with ERα and FOXA1 in a complex transcriptional regulatory program driving tumor growth. GATA3 mutations are frequent in breast cancer and have...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4021073/ https://ncbi.nlm.nih.gov/pubmed/24758297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-278 |
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