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Effect of TTP488 in patients with mild to moderate Alzheimer’s disease

BACKGROUND: TTP488, an antagonist at the Receptor for Advanced Glycation End products, was evaluated as a potential treatment for patients with mild-to-moderate Alzheimer’s disease (AD). A previous report describes decreased decline in ADAS-cog (delta = 3.1, p = 0.008 at 18 months, ANCOVA with multi...

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Detalhes bibliográficos
Main Authors: Burstein, Aaron H, Grimes, Imogene, Galasko, Douglas R, Aisen, Paul S, Sabbagh, Marwan, Mjalli, Adnan MM
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021072/
https://ncbi.nlm.nih.gov/pubmed/24423155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2377-14-12
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