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Optimal Auxiliary-Covariate Based Two-Phase Sampling Design for Semiparametric Efficient Estimation of a Mean or Mean Difference, with Application to Clinical Trials

To address the objective in a clinical trial to estimate the mean or mean difference of an expensive endpoint Y, one approach employs a two-phase sampling design, wherein inexpensive auxiliary variables W predictive of Y are measured in everyone, Y is measured in a random sample, and the semi-parame...

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Detalhes bibliográficos
Main Authors: Gilbert, Peter B., Yu, Xuesong, Rotnitzky, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021041/
https://ncbi.nlm.nih.gov/pubmed/24123289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.6006
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