Spontaneous Reversion of the Angiogenic Phenotype to a Non-angiogenic and Dormant State in Human Tumors

The angiogenic switch, a rate-limiting step in tumor progression, has already occurred by the time most human tumors are detectable. However, despite significant study of the mechanisms controlling this switch, the kinetics and reversibility of the process have not been explored. The stability of th...

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Bibliographic Details
Main Authors: Rogers, Michael S., Novak, Katherine, Zurakowski, David, Cryan, Lorna, Blois, Anna, Lifshits, Eugene, Bø, Trond H., Oyan, Anne M., Bender, Elise R., Lampa, Michael, Kang, Soo-Young, Naxerova, Kamila, Kalland, Karl-Henning, Straume, Oddbjorn, Akslen, Lars A., Watnick, Randolph S., Folkman, Judah, Naumov, George N.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020951/
https://ncbi.nlm.nih.gov/pubmed/24574516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-13-0532-T
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