Structure and Catalytic Regulatory Function of Ubiquitin Specific Protease 11 N-Terminal and Ubiquitin-like Domains

[Image: see text] The ubiquitin specific protease 11 (USP11) is implicated in DNA repair, viral RNA replication, and TGFβ signaling. We report the first characterization of the USP11 domain architecture and its role in regulating the enzymatic activity. USP11 consists of an N-terminal “domain presen...

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Detalhes bibliográficos
Main Authors: Harper, Stephen, Gratton, Hayley E., Cornaciu, Irina, Oberer, Monika, Scott, David J., Emsley, Jonas, Dreveny, Ingrid
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020902/
https://ncbi.nlm.nih.gov/pubmed/24724799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500116x
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