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Caffeine and Rolipram Affect Smad Signalling and TGF-β1 Stimulated CTGF and Transgelin Expression in Lung Epithelial Cells

Caffeine administration is an important part of the therapeutic treatment of bronchopulmonary dysplasia (BPD) in preterm infants. However, caffeine mediated effects on airway remodelling are still undefined. The TGF-β/Smad signalling pathway is one of the key pathways involved in airway remodelling....

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Détails bibliographiques
Auteurs principaux: Fehrholz, Markus, Speer, Christian P., Kunzmann, Steffen
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020861/
https://ncbi.nlm.nih.gov/pubmed/24828686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097357
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