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Apocynin attenuates ventilator-induced lung injury in an isolated and perfused rat lung model
RATIONALE: Apocynin suppresses the generation of reactive oxygen species (ROS) that are implicated in ventilator-induced lung injury (VILI). We thus hypothesized that apocynin attenuates VILI. METHODS: VILI was induced by mechanical ventilation with tidal volume (V(t)) of 15 ml/kg in isolated and pe...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4020846/ https://ncbi.nlm.nih.gov/pubmed/21618001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00134-011-2251-z |
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