Human Lung Epithelial Cells Contain Mycobacterium tuberculosis in a Late Endosomal Vacuole and Are Efficiently Recognized by CD8(+) T Cells

Mycobacterium tuberculosis (Mtb) is transmitted via inhalation of aerosolized particles. While alveolar macrophages are thought to play a central role in the acquisition and control of this infection, Mtb also has ample opportunity to interact with the airway epithelium. In this regard, we have rece...

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Autori principali: Harriff, Melanie J., Cansler, Meghan E., Toren, Katelynne Gardner, Canfield, Elizabeth T., Kwak, Stephen, Gold, Marielle C., Lewinsohn, David M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020835/
https://ncbi.nlm.nih.gov/pubmed/24828674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097515
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