High Molecular Weight Fibroblast Growth Factor-2 in the Human Heart Is a Potential Target for Prevention of Cardiac Remodeling

Fibroblast growth factor 2 (FGF-2) is a multifunctional protein synthesized as high (Hi-) and low (Lo-) molecular weight isoforms. Studies using rodent models showed that Hi- and Lo-FGF-2 exert distinct biological activities: after myocardial infarction, rat Lo-FGF-2, but not Hi-FGF-2, promoted sust...

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Detalhes bibliográficos
Main Authors: Santiago, Jon-Jon, McNaughton, Leslie J., Koleini, Navid, Ma, Xin, Bestvater, Brian, Nickel, Barbara E., Fandrich, Robert R., Wigle, Jeffrey T., Freed, Darren H., Arora, Rakesh C., Kardami, Elissavet
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020823/
https://ncbi.nlm.nih.gov/pubmed/24827991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097281
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