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High-Throughput Screening for Spermatogenesis Candidate Genes in the AZFc Region of the Y Chromosome by Multiplex Real Time PCR Followed by High Resolution Melting Analysis

Microdeletions in the AZF region of the Y chromosome are among the most frequent genetic causes of male infertility, although the specific role of the genes located in this region is not fully understood. AZFa and AZFb deletions impair spermatogenesis since no spermatozoa are found in the testis. De...

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Bibliografiske detaljer
Main Authors: Alechine, Evguenia, Corach, Daniel
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020812/
https://ncbi.nlm.nih.gov/pubmed/24828879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097227
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